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New amino alcohol derivatives, process for the production thereof and medicaments and reagents containing these compounds

机译:新的氨基醇衍生物,其生产方法以及含有这些化合物的药物和试剂

摘要

The present invention relates to new amino alcohol derivatives, process for the production thereof and medicaments and reagents containing these compounds. The subject of the invention is medicaments having the general formula (I) wherein A can mean hydrogen, a group NR1R2, a group NR1(CH2)pNR3R4, a group (C=NH)NH2 or a pyridinyl radical, B and D can be identical or different and stand each for a binding, a C1 to C6-alkylene radical or a group NR5-C2-C6-alkylene, C can mean piperidindiyl or piperazindiyl, W and X are identical or different and stand each for a carbonyl group, Y and Z can be identical or different and stand each for a saturated or unsaturated hydrocarbon radical with 7-24 carbon atoms, R1 to R5 can be identical or different and stand each for hydrogen or a C1 to C6 alkyl radical, m stands for a whole number 0, 1, or 2 and if m = 2 both radicals C independently from another can also mean piperidindiyl and piperazindiyl, n and o can be identical or different and stand each for a whole number 2, 3 or 4 and p means a whole number from 2 to 6, as well as their physiologically compatible salts, with the proviso that no hydrazine derivatives are comprised and that m be not 0, when A means hydrogen or a group (C=NH)NH2 and B and D are identical or different and represent a binding or an alkylene radical.
机译:本发明涉及新的氨基醇衍生物,其制备方法以及含有这些化合物的药物和试剂。本发明的主题是具有通式(I)的药物,其中A可以表示氢,基团NR1R2,基团NR1(CH2)pNR3R4,基团(C = NH)NH2或吡啶基,B和D可以是C 1至C 6-亚烷基或基团NR 5 -C 2 -C 6-亚烷基相同或不同,并且各自表示键合,C表示哌啶二基或哌嗪二基,W和X相同或不同,分别代表羰基, Y和Z可以相同或不同,分别代表具有7-24个碳原子的饱和或不饱和烃基,R1至R5可以相同或不同,分别代表氢或C1至C6烷基,m代表整数0、1或2,如果m = 2,两个基团C彼此独立也可以表示哌啶二基和哌嗪二基,n和o可以相同或不同,并且分别代表整数2、3或4,p表示a整数从2到6,以及它们的生理相容性盐,但前提是没有肼当A表示氢或基团(C = NH)NH 2且B和D相同或不同并表示键合或亚烷基时,包含衍生物且m不为0。

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