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Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment or prevention of diseases characterized by abnormal cell proliferation

机译:取代的二苯基茚满酮,茚满和吲哚化合物及其类似物可用于治疗或预防以细胞增殖异常为特征的疾病

摘要

The present invention provides substituted 3,3-diphenyl indanone, indane and indole compounds, as well as analogues thereof, which are specific, potent and safe inhibitors of mammalian cell proliferation. The compounds can be used to inhibit mammalian cell proliferation in situ as a therapeutic approach towards the treatment or prevention of diseases characterized by abnormal cell proliferation, such as cancer.
机译:本发明提供了取代的3,3-二苯基茚满酮,茚满和吲哚化合物及其类似物,它们是哺乳动物细胞增殖的特异性,有效和安全的抑制剂。所述化合物可用于原位抑制哺乳动物细胞增殖,作为治疗或预防以异常细胞增殖为特征的疾病如癌症的治疗方法。

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