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Assay method and device for detecting the presence and concentration of analyteswhile simultaneously preventing analyte adsorption to solid materials used in t he assay

机译:用于检测分析物的存在和浓度,同时防止分析物吸附到用于测定的固体材料中的测定方法和装置

摘要

This invention provides a method and a device for determining the presence and/or quantity of a hydrophobic analyte in a biological solution suspected of containing the analyte with enhanced sensitivity and precision. Sensitivity and precision of the method are achieved by selecting an antibody capable of binding to hydrophobic regions of the analyte, adding the selected antibody to the analyte before applying the solution containing the analyte to solid materials of the method and device, and hence, preventing adsorption of the analytes to the solid materials.
机译:本发明提供了一种方法和设备,用于以增强的灵敏度和精度确定在怀疑含有分析物的生物溶液中疏水性分析物的存在和/或数量。通过选择能够结合分析物的疏水区域的抗体,在将包含分析物的溶液施加到该方法和装置的固体材料上之前,将选择的抗体添加到分析物中,来实现该方法的灵敏性和精确性,从而防止吸附分析物到固体材料中

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