首页>
外国专利>
APPARATUS AND PROCESS FOR MONITORING AND DETECTING SMALL MOLECULE-BIOMOLECULE INTERACTIONS
APPARATUS AND PROCESS FOR MONITORING AND DETECTING SMALL MOLECULE-BIOMOLECULE INTERACTIONS
展开▼
机译:监测和检测小分子-生物分子相互作用的装置和方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
An apparatus (22) is provided for monitoring small molecule-biomolecule interactions. An oscillating substrate (10) has a wet surface (46) for contact with a liquid and for binding with a biomolecule and a dry surface (48). A detection apparatus (42, 44) determines the resonance frequency of said substrate before and after interaction. Thus, small molecules are monitored for interaction with biomolecules by contacting a solution containing the small molecule with immobilized biomolecules under test, and generating acoustic waves using an acoustic wave device. Interaction of the small molecules with the immobilized biomolecules causes a change in frequency, which can be detected and analyzed electronically to monitor the interaction.
展开▼