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CLONING AND CHARACTERIZATION OF THE CAP GENE PROMOTER

机译:CAP基因启动子的克隆和鉴定

摘要

The present invention relates to novel polynucleotides that contain peroxisome proliferator response elements (PPREs). The invention also describes vectors and host cells comprising the novel polynucleotides. The invention further describes methods for using the novel polynucleotides, gene therapy applications, diagnostics for syndromes involving insulin resistance, development of proprietary screening strategies for inhibitors of ligands or proteins that bind to, associate with, or interact with the CAP promoter.
机译:本发明涉及含有过氧化物酶体增殖物应答元件(PPRE)的新型多核苷酸。本发明还描述了包含新型多核苷酸的载体和宿主细胞。本发明进一步描述了使用新型多核苷酸的方法,基因治疗应用,涉及胰岛素抵抗的综合征的诊断,开发与CAP启动子结合,缔合或相互作用的配体或蛋白质抑制剂的专有筛选策略。

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