A rotary printing machine (1) comprising two supporting shoulders (3, 4), a central drum (2) or cylinder being rotatably mounted on the supporting shoulders, at least one printing unit (11) being arranged around the drum and comprising a printing plate cylinder (30) and an anilox roller (8), which are rotatably mounted on a respective pair of supporting elements and whose rotation axis is parallel to the axis of the drum, wherein at least the central drum is actuated by a source of motion (6) which directly engages an axial shank (9a) of the drum.
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