REGULATION OF HUMAN SEVEN TRANSMEMBRANE - LIKE G PROTEIN - COUPLED RECEPTOR (7TM-GPCR)

摘要

Reagents which regulate human seven transmembrane-like G protein-coupled receptor (7TM-GPCR) protein and reagents which bind to human 7TM-GPCR gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, infections such as bacterial, fungal, protozoan, and viral infections, particularly those caused by HIV viruses, pain, cancers, anorexia, bulimia, asthma, Parkinson's diseases, acute heart failure, hypotension, hypertension, urinary retention, osteoporosis, angina pectoris, myocardial infarction, ulcers, asthma, allergies, multiple sclerosis, benign prostatic hypertrophy, and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, several mental retardation, and dyskinesias, such as Huntington's disease and Tourett's syndrome.