SOLID, ORALLY ADMINISTERED, WATER-DISPERSIBLE PHARMACEUTICAL FORM FOR THE TREATMENT OF TUBERCULOSIS, CONTAINING RIFAMPICIN, ISONIAZID, PIRAZINAMIDE AND PYRIDOXINE HYDROCHLORIDE, METHOD FOR OBTAINING AND PRESENTATION FORM OF SAID PHARMACEUTICAL FORM

摘要

The pharmaceutical form contains rifampicin, isoniazid, pirazinamide and pyridoxine hydrochloride as active substances in a water-dispersible solid, granular matrix. Once reconstituted in water, said pharmaceutical gives rise to a pleasant tasting suspension. The method for obtaining said pharmaceutical form involves the following steps: simply mixing the components or separately obtaining rifampicin granules and isoniazid and pirazinamide granules and, optionally, pyridoxine hydrochloride granules; mixing and homogenizing said granules. The pharmaceutical form is suitable for preparing a presentation form of a medicament containing rifampicin, isoniazid, pirazinamide and pyridoxine hydrochloride, for example in the form of single dose envelopes containing said pharmaceutical form in a therapeutically effective dose.