COMPOSITIONS COMPRISING A MAST CELL DEGRANULATION-BLOCKING H-1 RECEPTOR ANTAGONIST FOR THE TREATMENT OF ENDOGENOUS, PAINFUL GASTROINTESTINAL CONDITIONS OF NON-INFLAMMATORY, NON-ULCERATIVE ORIGIN

摘要

A method for treating endogenous, painful gastrointestinal condition of non-inflammatory, non-ulcerative origin, such as abdominal migraine and irritable bowel syndrome, entails administering a pharmacologically effective amount of a mast cell degranulation-blocking agent, e.g. a histamine-3 receptor agonist.