Use of cytohesin-PH peptides to influence the adhesion capability of integrins

摘要

The following are new: (1) The cytohesin-2 peptide (A) with the 263 amino acid sequence (given in the specification); and (2) The use of a cytohesin PH peptide (B) for regulation of T-lymphocyte activation. Also claimed are: (3) DNA coding for at least part of (A); (4) use of (B)-encoding DNA for expression of (B); (5) use of a vector contg. the DNA of (4) for expression of (B); and (6) use of a host cell contg. the vector of (5).