TREATMENT OF CEREBRAL ISCHEMIA AND CEREBRAL DAMAGE WITH NEUROPROTECTIVE AGENT

摘要

PCT No. PCT/SE96/00036 Sec. 371 Date Jul. 11, 1997 Sec. 102(e) Date Jul. 11, 1997 PCT Filed Jan. 18, 1996 PCT Pub. No. WO96/22104 PCT Pub. Date Jul. 25, 1996The invention provides pharmaceutical compositions and medications useful for the treatment of cerebral ischernia, cerebral insult, and cerebral disorders using the active treatment medication cyclosporin A, variants or pharmaceutically acceptable derivatives thereof, inconditions, situations and methods wherein the blood-brain barrier has been opened, disrupted, bypassed, transgressed, obviated or crossed,such that cyclosporin A, variants or pharmaceutically acceptable derivatives thereof come into contact with neurons and neuron support cells. Included in the invention are methods for the use of the said pharmaceutical compositions and medications. Also included in the invention are conditions, situations and methods whereby the active treatment medication can come in contact with neurons and neuron support cells.