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CARDIOTROPIC RADIOPHARMACEUTICALS COMPRISING A TRANSITION METAL NITRIDE COMPLEX AND HAVING RAPID MYOCARDIAL CLEARANCE
CARDIOTROPIC RADIOPHARMACEUTICALS COMPRISING A TRANSITION METAL NITRIDE COMPLEX AND HAVING RAPID MYOCARDIAL CLEARANCE
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机译:包含过渡金属氮化物配合物并具有快速心肌清除作用的心型放射性药物
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摘要
Cardiotropic radiopharmaceuticals comprising a transition metal nitride complex and having rapid myocardial clearance are disclosed. The complexes have formula (I): (M N)L1 L2, wherein M is a transition metal such as: 99mTc, and L?1 and L2¿ have formula (II), wherein at least one of R and R' is a branched alkyl group comprising one or more ether functions, a tetrahydrofurfuryl or ether group or a tetrahydrofurfuryl or dioxaspiro or dialkoxy piperidino type group.
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机译:公开了包含过渡金属氮化物配合物并具有快速心肌清除率的心电放射性药物。该配合物具有式(I):(MN)L 1 L 2,其中M是诸如99mTc的过渡金属,并且L 1和L 2具有式(II),其中R和R'中的至少一个是支链的包含一个或多个醚官能团的烷基,四氢糠基或醚基或四氢糠基或二氧杂螺环或二烷氧基哌啶子基型基团。
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