ESTABLISHMENT OF HHV-8+ LYMPHOMA CELL LINE, VIRUS PRODUCED, ANTIBODY, DIAGNOSTIC METHOD AND KIT FOR DETECTING HHV-8 INFECTION

摘要

A method establishes for the first time a HHV-8 producing immortalized lymphoma cell line, which is free of EBV, CMV, and HIV. Large quantities of uncontaminated HHV-8 are produced by the cells, and the virus or immunogenic fragments thereof are used to obtain specific polyclonal and monoclonal antibody. Assays and kits are useful for detecting viral infection in mammalian samples.