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BIOSYNTHESIS OF FOREIGN PROTEINS USING TRANSFORMED MICROALGAE

机译:利用转化的微藻生物合成外源蛋白

摘要

The present invention relates to an economical method for biosynthesis of intended foreign proteins using transformed microalgae, that is to say, it relates to a method of using transformed microalgae as a bioreactor where economical biosynthesis of foreign protein is possible by transforming protoplast of microalgae such as iChlorella ellipsoidea/i with DNA vector containing intended foreign protein gene and then culturing it in a large scale. In particular, Sh ble gene, which is resistant to phleomycin, is used as a selection marker in the present invention.
机译:本发明涉及一种利用转化的微藻生物合成目的外来蛋白的经济方法,也就是说,它涉及一种使用转化的微藻作为生物反应器的方法,其中可以通过转化微藻的原生质体来经济地生物合成外来蛋白。用含有所需外源蛋白基因的DNA载体椭球藻,然后进行大规模培养。特别地,对毛霉素具有抗性的Sh ble基因在本发明中用作选择标记。

著录项

  • 公开/公告号EP1180145A1

    专利类型

  • 公开/公告日2002-02-20

    原文格式PDF

  • 申请/专利权人 ALGENETECH;

    申请/专利号EP20000911471

  • 发明设计人 CHOI TAE-JIN;KIM YOUNG-TAE;KIM DAE-HYUN;

    申请日2000-03-17

  • 分类号C12N15/18;

  • 国家 EP

  • 入库时间 2022-08-22 00:33:57

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