phenazine methosulfate for curing Benign Prostatic Hypertrophy

摘要

PURPOSE: Phenazine methosulfate capable of being used as a medicament having anti-benign prostatic hyperplasia activity or an inhibitor of testosterone 5-alpha-reductase is provided which can be effectively used in ameliorating benign prostatic hyperplasia when administered to human or animal in various types. CONSTITUTION: Phenazine methosulfate is used for inhibiting testosterone 5-alpha-reductase as a factor generating benign prostatic hyperplasia. Arthrobacter simplex strains are cultured in a tryptic soy broth medium, centrifuged and extracted with ethyl acetate, and the extract is concentrated, purified with thin layer chromatography, concentrated, dissolved in ethyl acetate, concentrated, dissolved in petroleum ether and concentrated to produce menaquinone 7.