-1 A novel obligately symbiotic thermophile Symbiobacterium toebii -1 producing thermostable L-tyrosine phenol-lyase and L-tryptophan indole-lyase and a method for screening its relative bacteria

摘要

The present invention relates to a novel high temperature symbiotic microorganism and a method for screening the same microorganisms that produce heat resistant tyrosine phenolase and tryptopanase. Specifically, the present invention relates to a novel high temperature symbiotic microorganism strainSymbiobacteriumcompostSC-1 (Symbiobacterium toebiiSC-1) is isolated and identified as the symbiotic partnerBacillusGenus SK-1 (Bacillussp. Without mixed culture with SK-1)Low-growth heat-resistant tyrosine phenolase and tryptopanase enzyme produced by pure culture aloneSymbiobacteriumcompostHow to measure the growth of SC-1 andSymbiobacteriumcompostThe present invention relates to a method for screening novel high temperature microorganisms similar to the strain using an antibody specific for SC-1. Of the present inventionSymbiobacteriumcompostHeat-resistant tyrosine phenolases and tryptopanases produced by SC-1 are more stable in bioconversion processes that enzymatically synthesize L-dihydroxy phenylalanine (L-DOPA) and L-tryptophan, both high-value pharmaceutical amino acids. May be provided as an enzyme.