CHALCONES AND THEIR COMPLICATED ETHERS OF ANTIPROLIFERATIVE ACTIVITY REGARDING UTERINE, OVARIAN AND MAMMARY GLAND TUMORS

摘要

FIELD: medicine, oncology. SUBSTANCE: the innovation deals with applying chalconic complicated ethers with direct and branched aliphatic acids, saturated and unsaturated, containing up to 22 carbon atoms in therapy and prophylaxis of uterine, ovarian and mammary gland tumors. Chalcones, such as isocordoin, cordoin, 2-hydroxyderricine, 2,4- dihydroxychalcone, 4,2,4-trihydroxychalcone have got considerable affinity to estrogenic receptors of type II and antiproliferative activity regarding linear cells of uterine, ovarian and mammary gland tumors. EFFECT: higher usefulness both in therapy and prophylaxis of such tumors. 3 cl, 2 tbl, 4 ex