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METHOD OF SYNTHESIS OF ALPHA-TOCOPHEROL (VITAMIN E)
METHOD OF SYNTHESIS OF ALPHA-TOCOPHEROL (VITAMIN E)
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机译:合成α-生育酚(维生素E)的方法
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摘要
FIELD: vitamins, chemical technology. SUBSTANCE: invention relates to the improved method of synthesis of α-tocopherol (vitamin E) that is a lipophilic antioxidant of mammal biological membranes. α-Tocopherol is synthesized by condensation of trimethylhydroquinone with racemic isophytol under condition of heterogeneous catalysis in the presence of zeolite-containing alumosilicate "Zeokar-10". The process is carried out at boiling in hydrocarbon or aromatic solvents (toluene, heptane, nonane) in the mole ratio trimethylhydroquinone : isophytol = 1:2 for 5-10 h. EFFECT: enhanced quantitative yield of end product due to use of "Zeokar-10". 4 ex
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