Use of enzyme inhibitors of dipeptidyl peptidase IV and aminopeptidase N and pharmaceutical preparations therefrom for the prevention and / or therapy of ischemia-related acute and chronic neurodegenerative processes and diseases

摘要

The invention includes a method in which, by the separate or joint administration and action of enzyme inhibitors of alanyl aminopeptidase (APN) and dipeptidyl peptidase IV (DP IV) or of enzymes of the same or similar substrate specificity, the damage to cerebral tissue as a result of ischemia or of a skull / brain trauma can be reduced or prevented. DOLLAR A Our invention shows that the separate or combined application of inhibitors of the above-mentioned enzymes or corresponding preparations and dosage forms thereof are suitable for the prevention and therapy of the above indications.