1,2-ETHANEDIOL DERIVATIVE OR SALT-CONTAINING POTENTIATOR OF THE ACTIVITY OF THE NERVOUS GROWTH FACTOR

摘要

A remedy for diseases caused by degeneration of central or peripheral nervous system, comprising a 1,2-ethanediol derivative represented by the following general formula or its salt: CHEM wherein R1 represents a substituted or unsubstituted phenyl, naphthyl, indanyl, indenyl, tetrahydronaphthyl or heterocyclic group; R2 represents a hydrogen atom, a lower alkyl group or a hydroxyl-protecting group; R3 represents a hydrogen atom or a lower alkyl group; nR4's may be the same as or different from one another and each represents a hydrogen atom or a lower alkyl group; nR5's may be the same as or different from one another and each represents a hydrogen atom or a lower alkyl group; R6 represents a substituted or unsubstituted amino or nitrogen-containing heterocyclic group or an ammonio group; and n represents 0 or an integer of 1 to 6.