medium with controlled release of the opposite micellare (l2) structure or a normal micellare (l1) structure form

摘要

PCT No. PCT/SE95/01479 Sec. 371 Date Apr. 29, 1997 Sec. 102(e) Date Apr. 29, 1997 PCT Filed Dec. 8, 1995 PCT Pub. No. WO96/17597 PCT Pub. Date Jun. 13, 1997A controlled-release composition for a biologically active material, characterized in that it comprises a mixture of: a) monocaproin, optionally in admixture with moncaprylin and/or monocaprin, and b) a polar liquid selected from the group consisting of such polar liquids which are capable of forming an L2 phase with a), and c) a biologically active material dissolved or dispersed in said mixture of a) and b), a) being present in the composition, based on the total weight of a)+b), in an amount of from the lower limit where the mixture of a) and b) forms a reversed micellar (L2) structure and up to 100% by weight of a), with the further proviso that said mixture of a) and b) is essentially within that specific domain of the L2 structure, in a phase diagram, where said L2 structure will change to a normal micellar (L1) structure if contacted with an external polar liquid. Said composition is preferably used as a medial composition.