Introduction vascular endothelial growth factor by serine / threonine protein kinase Akt of vascular endothelial growth factor (VEGF)

摘要

The present invention relates to methods and compositions for therapeutic angiogenesis. More especially, this invention is directed to induction of vascular endothelial growth factor (VEGF) expression by the serine/threonine protein kinase AKT. Preferably, the compositions and methods according to the invention comprise a nucleic acid encoding AKT, and administration thereof.