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Use of des-aspartate-angiotensin I as a therapeutic or prophylactic against glomerulosclerosis and renal failure
Use of des-aspartate-angiotensin I as a therapeutic or prophylactic against glomerulosclerosis and renal failure
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机译:天门冬氨酸血管紧张素I作为肾小球硬化症和肾功能衰竭的治疗或预防剂
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摘要
The present invention relates generally to a method for the treatment and/or prophylaxis of renal-related disorders. More particularly, the present invention contemplates a method for the treatment and/or prophylaxis of glomerulosclerosis and/or end stage renal failure and/or related conditions. The method of the present invention is preferably practised by the administration of a derivative of angiotensin I. Generally, but not exclusively, the angiotensin I derivative exhibits anti-angiotensin II properties. In a preferred embodiment, the angiotensin I is des-Aspartate-angiotensin I or a derivative, homologue or analogue thereof. The present invention further contemplates compositions for use in the treatment and/or prophylaxis of renal-related disorders such as but not limited to glomerulosclerosis and/or end stage renal failure.
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