The present invention includes ammonium salts and ions and formula (1):The present invention relates to a compound comprising a compound represented by the compounds (symbols in the formula), their ions and a group of pharmaceutically acceptable salts. Examples of the effective ingredient of the present invention include L-arginine and ethanolamine. The skin soundness agent according to the present invention has remarkable effects as a skin barrier mechanism, a function soundness agent, an atopic dermatitis prevention and a therapeutic agent.
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