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Method for treating extrauterine proliferation of endometrial tissue, chronic pelvic pain and fallopian tube obstruction

机译:治疗子宫内膜组织子宫外增生,慢性骨盆痛和输卵管阻塞的方法

摘要

The present invention provides a method for therapeutic management of extrauterine proliferation of endometrial tissue, chronic pelvic pain and fallopian tube obstruction by short term induction treatment with an LH-RH antagonist for 4 to 12 weeks. According to another aspect of the present invention, the short term LH-RH treatment is followed by the combined or separate administration of one or more active agents selected from the group consisting of a contraceptive, preferably an oral contraceptive, a non-steroidal anti-rheumatic agent, an analgetic, an androgen other than a 17-alpha-alkyl substituted testosterone or any combinations thereof. According to a further aspect of the present invention a pharmaceutical composition comprising an LHRH antagonist and one or more active agents selected from the group consisting of a contraceptive, preferably an oral contraceptive, a non-steroidal anti-rheumatic agent, an analgetic, an androgen other than a 17-alpha-alkyl substituted testosterone or any combinations thereof are provided.
机译:本发明提供了通过用LH-RH拮抗剂短期诱导治疗4至12周来子宫内膜组织子宫外增生,慢性骨盆痛和输卵管阻塞的治疗方法。根据本发明的另一方面,在短期LH-RH治疗之后,组合或分开施用选自避孕,优选口服避孕,非甾体类抗抑郁药的一种或多种活性剂。除17-α-烷基取代的睾丸激素以外的风湿药,止痛药,雄激素或其任意组合。根据本发明的另一方面,药物组合物包含LHRH拮抗剂和一种或多种选自避孕药,优选口服避孕药,非甾体类抗风湿药,镇痛药,雄激素的活性剂。除了17-α-烷基取代的睾丸激素或其任何组合以外,还提供了它们。

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