Determinable and non-invasive sensor of the optical parameters of a sample comprising a plurality of layers

摘要

(57) [Abstract] sample, in particular, an apparatus and method for measuring non-invasively at least one optical parameter of tissue samples comprising a plurality of layers. One optical parameter may be used to determine the presence or concentration of the analyte of interest in the tissue sample, at least. Measuring the light emitted substantially reflected from the shallower layers of the sample (1) tissue, scattering, absorption or apparatus and method of the present invention, substantially the deeper layers of the sample (2) Organization measuring the light emitted reflected, scattered, or absorbed, to determine the at least one optical parameter of each of the layers (3) these layers shallower than on the at least one optical parameter of the layer deeper than (4) consider the impact of. By specifying the sampling depth, specific layers of tissue samples, for example, it is possible to determine the optical properties of the dermis, other layers, for example, the stratum corneum, and interference from the skin is reduced in these decisions.