With enzyme disconnection physiology the magnetic resonance image modulo which uses the contrast medium professional drag which is activated

摘要

(57) Abstract This invention regards the contrast medium for diagnostic magnetic resonance image modulo. The chemical compound and the constituent of this application make the join of the contrast medium decrease for the target numerator, the disconnection possible chemical basis is included, to target it is form of the professional drag of the contrast medium which is converted. The professional drag of not yet disconnection has low compatibility vis-a-vis the target protein, and corresponds, shows low relief talent. Activation of the professional drag happens with enzyme disconnection. This it joins the contrast medium which is activated, with the target numerator, activity of the contrast medium and the target forms the complex. This activity the contrast medium after joining with the target protein, shows the relief talent which several times is higher than the professional drag of not yet disconnection. This the relief talent which augments improves contrast in the MRI image.