SECRETORY PROTEIN CREG2 EXPRESSING BRAIN-SPECIFIC EXPRESSION AND APPLICATION OF THE SAME

摘要

PROBLEM TO BE SOLVED: To obtain a substrate protein of deubiquitinating enzyme USP17 affected with brain-specific regulation and provide a genetic manipulation material for the same and the like.;SOLUTION: The excretion protein is the substrate protein of the deubiquitinating enzyme affected with the brain-specific regulation. Human secretory protein CREG2 having a specific amino acid sequence, mouse protein Creg2 having another specific amino acid sequence, genom DNA, mRNA, cDNA of human gene, those of mouse gene and polynucleotides purified from complementary arrangements of those are claimed.;COPYRIGHT: (C)2003,JPO