FUSED PEPTIDE OF PEPTIDE DERIVED FROM C-TERMINUS OF HUMAN COLLAGEN TYPE I TO WHICH TAT PEPTIDE IS LINKED, METHOD OF PRODUCING THE SAME AND SKIN WRINKLE-IMPROVING COSMETIC COMPOSITION CONTAINING THE SAME

摘要

PROBLEM TO BE SOLVED: To provide a peptide that is readily absorbed through skin and shows enhanced wrinkle alleviation effect in living body and a method of producing the same.;SOLUTION: The peptide is a fused polypeptide prepared by linking an autocytopermeating Tat peptide having an auto-permeation signal to a peptide derived from the C-terminus of human collagen type I. A method of producing the same and a cosmetic composition for alleviating skin wrinkles.;COPYRIGHT: (C)2004,JPO