METHOD FOR PRODUCING ENANTIOMER-CONCENTRATED AMINO ACID AND RACEMIZATION METHOD AND METHOD FOR CREAVING PROTECTING GROUP OF N-PROTECTED AMINO ACID, AND USE OF OBTAINED AMINO ACID

摘要

PROBLEM TO BE SOLVED: To provide a method for producing an optically concentrated amino acid from the racemate mixture of the amino acid protected with a urethane or carbamoyl protecting group.;SOLUTION: This method for producing the enantiomer-concentrated amino acid is characterized by reacting a compound of formula (I) (X is O or NH; R¹ is CH₃, CH₃CH₂, tert-butyl, or benzyl, provided that R¹ may be H, when X is NH; R² is the α-group of a natural or synthetic amino acid) with an enzyme exhibiting an N-acetylamino acid racemase activity (AAR) in the presence of an enzyme exhibiting an amino acid acylase activity or then with the enzyme exhibiting an amino acid acylase activity.;COPYRIGHT: (C)2003,JPO