COMBINATIONAL PHARMACEUTICAL TREATMENT FOR SLEEP DISORDER INCLUDING SLEEP APNEA

摘要

PROBLEM TO BE SOLVED: To obtain a pharmaceutical composition for the treatment of sleep disorder including sleep apnea of a mammal including a human being. SOLUTION: This pharmaceutical composition comprises (a) an arylalkylamine being a SRI(serotonin reuptake inhibitor) antidepressant, (b) a 5HTla antagonist or an alpha-2-adrenergic antagonist (pindolol etc.), and (c) a pharmaceutically acceptable carrier and has an improved efficacy by the combination of the active substances (a) and (b).