Treatment of movement disorders with metabotropic glutamate receptors antagonist

摘要

The present invention relates to the use of compounds, which inhibit metabotropic glutamate receptor activity, or activation, for use in the treatment of movement disorders associated with a poverty of movement (e.g. Parkinson's disease). The compounds are particularly useful when used in combination with another therapeutic agent and surprisingly reduce the extent and incidence of side effects (e.g. dyskinesia) associated with such therapeutic agents.