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Use of DF3/MUC1 regulated expression in gene therapy
Use of DF3/MUC1 regulated expression in gene therapy
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机译:DF3 / MUC1调控表达在基因治疗中的应用
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摘要
The present invention provides for improved vectors for use in gene therapy. Utilizing the cancer specific DF3/MUC1 promoter to drive a replication essential gene, vectors are made conditionally replication-competent, permitting wider infection and expression of tumor cells. In addition, therapeutic genes and adjunct therapies further increase anti-tumor efficacy.
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