TARGETS OF THE MAP KINASE PATHWAY IN THE DEVELOPMENTAL SWITCH IN YEAST

摘要

Assessment of targets of the MAP kinase pathway in the developmental switch between haploid invasive growth and diploid pseudohyphal development in fungi, and identification of genes that show strong regulation by a MAPK pathway-specific transcription factor, Tec1, are described. Also described are methods of identifying an agent which inhibits the filamentation MAPK pathway in a fungus, and methods of inhibiting filamentation of a fungus or invasion of a host by a fungus.