Transgenic mice containing ubiquitin protein ligase E3 gene disruptions
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机译:转基因小鼠含有泛素蛋白连接酶E3基因破坏
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摘要
The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in an ubiquitin ligase E3 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
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