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Human KCR1 regulation of HERG potassium channel block
Human KCR1 regulation of HERG potassium channel block
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机译:人类KCR1对HERG钾通道阻滞的调节
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摘要
The present invention discloses methods relating to screening methods and methods of identifying a compound that can modulate HERG potassium channel activity. The methods generally employ at least HERG and KCR1 polypeptides. The disclosed methods can be applied in the development of a candidate pharmaceutical or they can be employed to evaluate presently marketed pharmaceuticals.
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