Transmembrane protein differentially expressed in prostate and lung tumors

摘要

The invention provides a cDNA which encodes a transmembrane protein differentially expressed in prostate and lung cancer. It also provides for the use of the cDNA, fragments, complements, and variants thereof and of the encoded protein, portions thereof and antibodies thereto for diagnosis and treatment of cancer, in particular, prostate or lung cancers. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic model system.