首页> 外国专利> Combination of treatment of cancer utilizing a COX-2 inhibitor and a 3-hydroxy-3-methylglutaryl-coenzyme-a (HMG-CoA) reductase inhibitor

Combination of treatment of cancer utilizing a COX-2 inhibitor and a 3-hydroxy-3-methylglutaryl-coenzyme-a (HMG-CoA) reductase inhibitor

机译:利用COX-2抑制剂和3-羟基-3-甲基戊二酰辅酶A(HMG-CoA)还原酶抑制剂联合治疗癌症

摘要

The inventors propose a combination of an HMG-CoA reductase inhibitor (also referred to as “HMG-CoA inhibitor(s)”), and COX-2 inhibitor for the treatment of cancer especially prostate cancer and a method of treatment of cancer by that combination, especially prostate cancer. The inventors propose a combination of an HMG-CoA reductase inhibitor, COX-2 inhibitor, and glutathione pathway enhancing and detoxifying compound, particularly cystine, for the treatment of cancer especially prostate cancer and a method of treatment of cancer by that combination, especially prostate cancer. Based on the clinical results of retardation, but not cure of cancer, the combination has the characteristic of sufficiently interfering with replication and apparently restoring the immune system capacity to manage cancer.
机译:发明人提出了用于治疗癌症特别是前列腺癌的HMG-CoA还原酶抑制剂(也称为“ HMG-CoA抑制剂”)和COX-2抑制剂的组合以及癌症的治疗方法通过这种组合,尤其是前列腺癌。发明人提出了用于治疗癌症特别是前列腺癌的HMG-CoA还原酶抑制剂,COX-2抑制剂和谷胱甘肽途径增强和解毒化合物,特别是胱氨酸的组合,以及通过该组合特别是前列腺的癌症治疗方法癌症。基于延迟而不是治愈癌症的临床结果,该组合具有充分干扰复制并明显恢复免疫系统控制癌症的能力的特征。

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