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NOVEL METHODS FOR TESTING INHIBITORS OF PAIRED HELICAL FILAMENTS AND USES FOR TREATMENT OF ALZHEIMER'S DISEASE
NOVEL METHODS FOR TESTING INHIBITORS OF PAIRED HELICAL FILAMENTS AND USES FOR TREATMENT OF ALZHEIMER'S DISEASE
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机译:测试螺旋状长丝抑制剂的新方法以及用于治疗老年痴呆症的方法
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摘要
The present invention relates to the use of inhibitors of intracellular polyanions, for example of RNA or polyanionic polypeptides, or derivatives thereof for the prevention or treatment of Alzheimer disease. In addition, the present invention relates to methods for testing inhibitors for their capacity to inhibit PHF formations and to kits useful in carrying out such methods.
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