Ozonated medical devices and methods of using ozone to prevent complications from indwelling medical devices

摘要

Indwelling medical devices resistant to microbial colonization and other complications include devices having a coating on one or more surfaces comprising an effective amount or concentration of an oxygen liberating substance, such as ozone, and optionally, one or more other therapeutic agents. Devices may alternately include a sleeve or other means which allows one or more surfaces of the device to be flushed or insufflated periodically with ozone or another oxygen liberating substance.