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Malleable putty and flowable paste with allograft bone having residual calcium for filling bone defects
Malleable putty and flowable paste with allograft bone having residual calcium for filling bone defects
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机译:具有同种异体移植骨的可塑腻子和可流动糊状物,具有残留钙以填充骨缺损
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摘要
The invention is directed toward a malleable bone putty and a flowable pastel composition for application to a bone defect site to promote new bone growth at the site which comprises a new bone growth inducing compound of partially demineralized lyophilized allograft bone material having a residual calcium content ranging from 4 to 8% dry weight. The bone powder has a particle size ranging from about 100 to about 800 microns and is mixed in a high molecular weight hydrogel carrier containing a sodium phosphate saline buffer, the hydrogel component of the carrier ranging from about 1.00 to 50% of the composition and having a molecular weight of about at least 700,000 Daltons. The composition has a pH between 6.8-7.4 contains about 25% to about 35% bone powder and can be additionally provided with BMP's.
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