首页>
外国专利>
Combinations of heparin cofactor II agonist and platelet IIb/IIIa antagonist, and uses thereof
Combinations of heparin cofactor II agonist and platelet IIb/IIIa antagonist, and uses thereof
展开▼
机译:肝素辅因子Ⅱ激动剂和血小板Ⅱb/Ⅲa拮抗剂的组合及其用途
展开▼
页面导航
摘要
著录项
相似文献
摘要
Combined use of a heparin cofactor II agonist and a platelet GPIIb/IIIa receptor antagonist to inhibit both platelet aggregation and thrombin generation resulting from disease, injury or responses to wound repairs. The combined use of the heparin cofactor II agonist and the platelet GPIIb/IIIa receptor antagonist can achieve these therapeutic benefits while at the same time minimizing or reducing the risk of hemorrhagic side effects (e.g., prolonged bleeding), and without causing undesired antigenic responses. Moreover, certain subtherapeutic amounts of the heparin cofactor II agonist with certain subtherapeutic amounts of a platelet GPIIb/IIIa receptor antagonist can, in combination, be therapeutically effective in inhibiting both platelet aggregation and thrombin generation.
展开▼