embedded image;having pharmacological activity, to processes for their preparation, to a combinatorial library and solid phase methods for preparing libraries of the compounds, to utilizing libraries of the compounds for drug discovery, and to pharmaceutical compositions thereof."/> Methods for the solid phase synthesis of 2-amino-4(H)-quinazolinone derivatives
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Methods for the solid phase synthesis of 2-amino-4(H)-quinazolinone derivatives

机译:固相合成2-氨基-4(H)-喹唑啉酮衍生物的方法

摘要

The present invention relates to solid phase synthesis of substituted 2-amino-4(H)-quinazolinone compounds of formula (I): embedded image;having pharmacological activity, to processes for their preparation, to a combinatorial library and solid phase methods for preparing libraries of the compounds, to utilizing libraries of the compounds for drug discovery, and to pharmaceutical compositions thereof.
机译:本发明涉及式(I)的取代的2-氨基-4(H)-喹唑啉酮化合物的固相合成:<化学ID =“ CHEM-US-00001”> <图像alt =“嵌入式图像” file =“ US06525061-20030225-C00001.GIF“ he =” 78.0192“ id =” EMI-C00001“ imgContent =” undefined“ imgFormat =” GIF“ wi =” 177.1308“ /> ;具有药理活性的化合物,其制备方法,组合库和用于制备化合物库的固相方法,利用化合物的库进行药物发现及其药物组合物。

著录项

  • 公开/公告号US6525061B1

    专利类型

  • 公开/公告日2003-02-25

    原文格式PDF

  • 申请/专利权人 WYETH;

    申请/专利号US20000711795

  • 发明设计人 ARIAMALA GOPALSAMY;HUI Y. YANG;

    申请日2000-11-10

  • 分类号A61K315/17;C07D2399/50;

  • 国家 US

  • 入库时间 2022-08-22 00:05:29

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