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Radioactive intraluminal endovascular prothesis and method for the treatment of aneurysms

机译:放射性腔内血管内假体及治疗动脉瘤的方法

摘要

A method for increasing the rate of thrombus formation and/or proliferative cell growth of a selected region (21) of cellular tissue (22) including the step of endovascularly irradiating the selected region (21) with radiation, having a dose range of endovascular radiation of about 1 Gy to about 600 Gy at a low dose rate of about 1 cGy/hr to about 320 cGy/hr, to increase thrombus formation and/or cell proliferation of the affected selected region (21). Preferably, the delivery means includes a deformable endovascular prosthesis (25) adapted for secured positioning adjacent to the selected region (21) of cellular tissue (22), and a radioactive source. This source cooperates with the deformable endovascular device (25) in a manner endovascularly irradiating the selected region with radiation, having the above-indicated dose range and low dose rate of endovascular radiation to increase thrombus formation and/or cell proliferation of the affected selected region (21).
机译:增加细胞组织( 22 )选定区域( 21 )的血栓形成和/或增生细胞生长速率的方法,包括血管内照射选定的步骤具有辐射的区域( 21 ),在约1 cGy / hr至约320 cGy / hr的低剂量率下具有约1 Gy至约600 Gy的血管内辐射剂量范围,以增加血栓形成受影响区域( 21 )的形成和/或细胞增殖。优选地,输送装置包括可变形的血管内假体( 25 ),其适于牢固定位在细胞组织( 22 的选定区域( 21 )附近。 >)和放射源。该源与可变形的血管内装置( 25 )配合使用,以上述方式在血管内向选定区域进行放射线照射,具有上述剂量范围和较低的血管内放射剂量率,以增加血栓形成和/或受影响的选定区域( 21 )的细胞增殖。

著录项

  • 公开/公告号US6554758B2

    专利类型

  • 公开/公告日2003-04-29

    原文格式PDF

  • 申请/专利权人 ISOSTENT INC.;

    申请/专利号US20010755735

  • 发明设计人 TODD H. TURNLUND;WILLIAM L. SWEET;

    申请日2001-01-05

  • 分类号A61N50/00;

  • 国家 US

  • 入库时间 2022-08-22 00:05:20

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