首页>
外国专利>
Method of and apparatus for selective collision-induced dissociation of ions in a quadrupole ion guide
Method of and apparatus for selective collision-induced dissociation of ions in a quadrupole ion guide
展开▼
机译:在四极离子导向器中离子选择性碰撞诱导解离的方法和装置
展开▼
页面导航
摘要
著录项
相似文献
摘要
A method and apparatus are provided for selective collision-induced dissociation of a substance, by resonance excitation of ions. An ion stream is supplied into a quadrupole ion guide operated at elevated pressure with a buffer gas. In addition to a radio frequency field for guiding ions through the ion guide, an extra field or other excitation is provided. This field is selected to cause resonance excitation of parent ions of interest. These ions gain kinetic energy and undergo enhanced collision-induced dissociation with a buffer gas. This generates fragment ions, so that the resultant ion stream, containing remaining parent ions and fragment ions can be analyzed in a suitable analyzer. The method essentially enables the two steps of selection of a particular parent ion and generation of fragment ions by collision-induced dissociation to be carried out in a single step, giving a simpler apparatus and enhanced efficiency.
展开▼