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Method of detecting anti-Chlamydia pneumoniae antibody using Chlamydia pneumoniae-specific antigens
Method of detecting anti-Chlamydia pneumoniae antibody using Chlamydia pneumoniae-specific antigens
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机译:使用肺炎衣原体特异性抗原检测抗肺炎衣原体抗体的方法
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摘要
Chlamydia pneumoniae antigenic polypeptides, which comprise polypeptide A containing a sequence of at least 5 consecutive amino acids in the polypeptide of SEQ ID NO: 1, DNAs encoding the antigenic polypeptides, or DNAs complementary thereto; a method for detection and/or measurement of an anti-Chlamydia pneumoniae antibody, wherein the antigenic polypeptide is used as an antigen; reagents for detection and/or measurement of an anti-Chlamydia pneumoniae antibody, which comprise the antigenic polypeptide as an antigen; agents for diagnosis of Chlamydia pneumoniae infections, which comprise the antigenic polypeptide as an active ingredient; fused proteins of an antigenic polypeptide of Chlamydia pneumoniae with dihydrotolate reductase, in which polypeptide A containing a sequence of at least 5 consecutive amino acids in the polypeptide of SEQ ID NO: 1 is bound to the polypeptide of SEQ ID NO: 14 either directly or via an intervening amino acid or amino acid sequence; DNAs encoding the fused proteins, or DNAs complementary thereto.
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机译:肺炎衣原体抗原多肽,其包含在SEQ ID NO:1的多肽中包含至少5个连续氨基酸序列的多肽A;编码抗原性多肽的DNA或与其互补的DNA;和一种检测和/或测量抗肺炎衣原体抗体的方法,其中所述抗原性多肽用作抗原;用于检测和/或测量抗肺炎衣原体抗体的试剂,其包含抗原性多肽作为抗原; 肺炎衣原体感染的诊断试剂,其包含抗原多肽作为活性成分;衣原体肺炎衣原体抗原多肽与二氢甲苯磺酸还原酶的融合蛋白,其中SEQ ID NO:1多肽中含有至少5个连续氨基酸序列的多肽A与SEQ ID NO:1的多肽结合ID NO:14直接或通过插入的氨基酸或氨基酸序列;编码融合蛋白的DNA或与其互补的DNA。
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