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Antibodies that bind to amp;agr;2-antiplasmin crosslinked to fibrin which do not inhibit plasma amp;agr;2-antiplasmin
Antibodies that bind to amp;agr;2-antiplasmin crosslinked to fibrin which do not inhibit plasma amp;agr;2-antiplasmin
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机译:与α2-抗纤溶酶结合的抗体与血纤蛋白交联,不会抑制血浆α2-抗纤溶酶
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摘要
The present invention relates to a treatment for myocardial infarction and blood clots within a patient, and more specifically to a therapy which enhances clot lysis comprising administering to a patient an antibody directed to &agr;2-antiplasmin crosslinked to fibrin (&agr;2AP-FX) which does not inhibit plasma &agr;2-antiplasmin (&agr;2AP). The invention also relates to a treatment for enhancing clot lysis comprising administering an antibody directed toward &agr;2-antiplasmin crosslinked to fibrin which does not inhibit plasma &agr;2AP together with a thrombolytic agent.
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