首页> 外国专利> Peptides useful for preparing Medicines for the treatment, prevention or amelioration of allergic States Epitopes, immunogens and Vaccines, ligands, mimotopePharmaceutical compositions of peptides; use of the ligands in the Preparation Process to prepare Vaccines and medicines; pr

Peptides useful for preparing Medicines for the treatment, prevention or amelioration of allergic States Epitopes, immunogens and Vaccines, ligands, mimotopePharmaceutical compositions of peptides; use of the ligands in the Preparation Process to prepare Vaccines and medicines; pr

机译:用于制备药物的肽,用于治疗,预防或改善过敏状态的药物表位,免疫原和疫苗,配体,模拟表位肽的药物组合物;配体在制备过程中用于制备疫苗和药物的用途;公关

摘要

Describes these Medicines for the treatment, prevention or Improvement of allergies.In particular, New drugs are isolated peptides containing epitopes or mimotope of Regions exposed to the surface of the epsilon2 C domain of IgE.The Inventors have found that these new portions may be the target of both Active and passive immunoprophylaxis or Immunotherapy.Specifically it is characterized in that it comprises a Peptide isolated or isolated HIV epitope exposed on the surfaces of C epsilon2 domain of IgE.The Invention also relates to processes for the production of Medicines, the pharmaceutical compositions containing them and their use in Medicine.Also give rise to an aspect of the present Invention ligands especially Monoclonal AntibodiesYou are able to join the regions of IgG exposed at the surface of the Invention and their use in medicine as Passive immunoprophylaxis or Immunotherapy.
机译:描述这些用于治疗,预防或改善过敏的药物,特别是新药物是含有暴露于IgE epsilon2 C结构域表面的区域的表位或模拟表位的分离肽。发明人发现这些新部分可能是主动和被动免疫预防或免疫疗法的靶标。特别地,其特征在于,其包含暴露于IgE的C epsilon2结构域表面的肽分离的或分离的HIV表位。本发明还涉及药物的生产方法,所述药物包含它们的组合物及其在医学中的用途。还产生了本发明的一个方面,配体,尤其是单克隆抗体,您可以连接暴露在本发明表面的IgG区域,以及它们在医学中作为被动免疫预防或免疫疗法的用途。

著录项

  • 公开/公告号AR029336A1

    专利类型

  • 公开/公告日2003-06-25

    原文格式PDF

  • 申请/专利号AR2000P100820

  • 发明设计人

    申请日2000-02-25

  • 分类号C07K16/00;C07K16/42;A61K39/00;A61K39/385;A61K39/395;G01N33/577;G01N33/68;A61P37/08;

  • 国家 AR

  • 入库时间 2022-08-22 00:04:05

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