Morfolinobenzamida pharmaceutically acceptable Salt or solvate thereof, Pharmaceutical composition containing IT, its use for the manufacture of a Medicament and Process for preparing the Salt or solvate

摘要

A pharmaceutically acceptable formulation (1) a salt or a salt solution of a morphine amide compound, wherein the formulation compound (1) is a corresponding isomer (R),And - hydrogen (4-hydrogen-phenyl-4-phenyl-4-4]]] - [Third] treatment - [Third] sink (methylene, third (4methyperazin-1-il) - 1, 2, 3, 4, -Tetrahydro-2-naftil] - 4-morphine imide (R) - N - [5-methyl-8 - (4-methylpiperazin-1-il) - 1,2,3,4-tetrahydro-2-naftil] - 4(r) - N - [5-methyl-8 - (4-methylpyridine-1-il) - 1, 2, 3, 4-tetrahydro-2-naphthalene] - 4 (R) Aminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminaminamide-4-hydroxyhydrofluorocarbon-4 (r) - N - [5-methyl-8 - (4-methyl-pyridine-1-il) - 1, 2, 3, 4-tetrahydro-2-naphthalene] - 4-fluorodiphenylsulfonate, (R) - N - [5-methyl-8 (4-methylpyridine-1-il) - 1, 2, 3, 4-tetrahydro-2-nafti] - 4(r) - N - [5-methyl-8 - (4-methylpyridine-i-il) - 1,2,3,4-tetrahydro-2-naphthalene] - 4-morphoxybenzodihydroxyhydrazide citrate y (R) - N - [5-methyl-8 - (4-methylpyridine-1-il) - 1,2,3,4-tetrahydro-2-nafti] - 4 Drug formulations containing these active therapeutic compounds and the production of drugs using these active compounds. They are compounds used for therapeutic purposes, in particular those with a selective effect on the 5-hydroxymethamphetamine receptor group designated as the h5-htib receptor (formerly known as the 5-HT (1dbeta) receptor in mammals, including humans,Its compounds are easy to form in drug combinations. They are compounds with therapeutic effects after oral administration.