Compounds of quinazoline ditosylate, Pharmaceutical composition, method of treatment and use in therapy and Process for the preparation of these compounds

摘要

Describes the ditosylate salts of the 4 - quinazolinaminas as well as Methods of using them in the treatment of disorders characterized by Aberrant PTK activity of the ErbB Family. In particular are described compounds of formula (1), Anhydrate forms hydrate or the same where R1 is cl or BR; X is n or ch and CF; Het is thiazole or Furan.It also describes compositions containing Said compounds and the use thereof in the preparation of medicines.